EFFECT OF PROPRANOLOL PHENTOLAMINE AND PIMOZIDE ON DRUG-INDUCED ANOREXIA IN THE MOUSE

被引：17
|
作者：
DOBRZANSKI, S [1 ]
DOGGETT, NS [1 ]
机构：
[1] UWIST,WELSH SCH PHARM,DEPT PHARMACOL,CARDIFF CF1 3NU,S GLAMORGAN,WALES
来源：
PSYCHOPHARMACOLOGY | 1979年 / 66卷 / 03期
关键词：
(+)Amphetamine; Diethylproprion; Dopaminergic receptors; Mazindol; Noradrenergic receptors; Phentermine;
D O I：
10.1007/BF00428323
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Pimozide was a potent antagonist of (-)amphetamine, diethylpropion, mazindol and phentermine anorexia in the mouse. Phentolamine and propranolol produced no such antagonism, but either potentiated or had no effect on the drug-induced anorexia. Although the mechanism of action of the four anorectic agents appears to involve dopamine receptor agonist activity, an antagonist or partial agonist effect at noradrenergic receptors may also be involved. © 1979 Springer-Verlag.
引用
收藏
页码：297 / 300
页数：4
相关论文
共 43 条
  • [1] EFFECTS OF CIRCADIAN CYCLE AND TIME OF TESTING ON DRUG-INDUCED ANOREXIA IN RATS
    DAVIES, BT
    WELLMAN, PJ
    BEHAVIOURAL PHARMACOLOGY, 1991, 2 (03): : 199 - 204
  • [2] The effect of previous exposure to amphetamine on drug-induced locomotion and self-administration of a low dose of the drug
    Vezina, P
    Pierre, PJ
    Lorrain, DS
    PSYCHOPHARMACOLOGY, 1999, 147 (02) : 125 - 134
  • [3] Drug-induced bilateral ischemic infarction in an amphetamine addict
    Martin R. Christensen
    Iana Lesnikova
    Line B. Madsen
    Ingrid Rosendal
    Jytte Banner
    Forensic Science, Medicine, and Pathology, 2013, 9 : 458 - 461
  • [4] Drug-induced delusion: A comprehensive overview of the WHO pharmacovigilance database
    Balcerac, Alexander
    Baldacci, Antoine
    Romier, Alix
    Annette, Sophie
    Lemarchand, Baptiste
    Bihan, Kevin
    Bottemanne, Hugo
    PSYCHIATRY RESEARCH, 2023, 327
  • [5] Striatal transcriptome changes linked to drug-induced repetitive behaviors
    Crittenden, Jill R.
    Gipson, Theresa A.
    Smith, Anne C.
    Bowden, Hilary A.
    Yildirim, Ferah
    Fischer, Kyle B.
    Yim, Michael
    Housman, David E.
    Graybiel, Ann M.
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2021, 53 (08) : 2450 - 2468
  • [6] Evaluating Predominant Causes of Insanity in Cases of Drug-Induced Psychoses
    Wondemaghen, Meron
    INTERNATIONAL JOURNAL OF FORENSIC MENTAL HEALTH, 2015, 14 (01) : 76 - 84
  • [7] Drug-induced stimulation and suppression of action monitoring in healthy volunteers
    Ellen R. A. de Bruijn
    Wouter Hulstijn
    Robbert J. Verkes
    Gé S. F. Ruigt
    Bernard G. C. Sabbe
    Psychopharmacology, 2004, 177 : 151 - 160
  • [8] Ice water submersion for rapid cooling in severe drug-induced hyperthermia
    Laskowski, Larissa K.
    Landry, Adaira
    Vassallo, Susi U.
    Hoffman, Robert S.
    CLINICAL TOXICOLOGY, 2015, 53 (03) : 181 - 184
  • [9] THE DESCRIPTION OF RAT DRUG-INDUCED BEHAVIOR - KINEMATICS VERSUS RESPONSE CATEGORIES
    ADANI, N
    KIRYATI, N
    GOLANI, I
    NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 1991, 15 (04) : 455 - 460
  • [10] Natural segmentation of the locomotor behavior of drug-induced rats in a photobeam cage
    Kafkafi, N
    Mayo, C
    Drai, D
    Golani, I
    Elmer, G
    JOURNAL OF NEUROSCIENCE METHODS, 2001, 109 (02) : 111 - 121
12345