IN-VITRO EVALUATION OF A NEW FILTER FOR LEUKOCYTE DEPLETION OF PLATELET CONCENTRATE DURING COMPONENT PREPARATION

被引：4
作者：
CHRISTENSEN, LD
DICKMEISS, E
机构：
[1] Department of Clinical Immunology, Rigshospitalet, University Hospital, Blood Bank, Copenhagen
来源：
VOX SANGUINIS | 1994年 / 67卷 / 03期
关键词：
D O I：
10.1111/j.1423-0410.1994.tb01249.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A newly developed filter for prestorage leucocyte depletion of platelet concentrates (PC) was studied. The filter is designed for leucocyte depletion during the preparation of the pool PC from platelet rich buffy coats. In all the leucocyte depleted PC (LD-PC) leucocyte depletion was satisfactory. 19 of 20 units of LD-PC had a leucocyte content below 3 x 10(5) per PC and 1 contained 8 x 10(5) leucocytes. The standard PC contained 2.53 x 10(8) (0.87 x 10(8)-15.3 x 10(8); n = 20) leucocytes per PC (median and range). The quality of the LD-PC was evaluated by measuring platelet activation, platelet morphology, and pre- and poststorage pH. There were no differences in any of the parameters studied.
引用
收藏
页码：267 / 271
页数：5
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