EXTINCTION OF GENE-EXPRESSION IN SOMATIC-CELL HYBRIDS - A REFLECTION OF IMPORTANT REGULATORY MECHANISMS

被引：47

作者：

BOSHART, M ^{[1
]}

NITSCH, D ^{[1
]}

SCHUTZ, G ^{[1
]}

机构：

[1] GERMAN CANC RES CTR,DIV MOLEC BIOL CELL 1,W-6900 HEIDELBERG 1,GERMANY

来源：

TRENDS IN GENETICS | 1993年 / 9卷 / 07期

关键词：

D O I：

10.1016/0168-9525(93)90088-Y

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell differentiation.

引用

页码：240 / 245

页数：6

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