Objective: The aim of this review is to provide pharmacists a practical information to guide consumers in their choices of herbal products for the management of DM2. Material and Methods: An exhaustive search of the published literature in referencial data recourses was performed, up to March 31nd 2015. Revisions and selected studies were subjected to critical reading and assessment of methodological quality. Results: Pharmacist advice is often requested on the use of these agents for the management of type 2 diabetes mellitus (DM2); however, this is an area that has insufficient evidence to support confident recommendations. Many published studies involving herbal agents are small and poorly designed, with heterogeneous results. Conclusion: The strongest scientific evidence for blood glucose lowering effect is associated with fenugreek. There is also good evidence supporting the use of ivy gourd and gymnema for management of hyperglycemia.