NG-MONOMETHYL-L-ARGININE DOES NOT INHIBIT THE HINDQUARTERS VASODILATOR ACTION OF ENDOTHELIN-1 IN CONSCIOUS RATS

被引:52
作者
GARDINER, SM [1 ]
COMPTON, AM [1 ]
BENNETT, T [1 ]
PALMER, RMJ [1 ]
MONCADA, S [1 ]
机构
[1] WELLCOME RES LABS,BECKENHAM BR3 3BS,KENT,ENGLAND
关键词
D O I
10.1016/0014-2999(89)90113-1
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:237 / 240
页数:4
相关论文
共 10 条
[1]  
DENUCCI G, 1988, P NATL ACAD SCI USA, V85, P9797
[2]  
GARDINER S, IN PRESS BR J PHARM
[3]   REGIONAL HEMODYNAMIC-EFFECTS OF ENDOTHELIN-1 IN CONSCIOUS, UNRESTRAINED, WISTAR RATS [J].
GARDINER, SM ;
COMPTON, AM ;
BENNETT, T .
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1989, 13 :S202-S204
[4]   REGIONAL BLOOD-FLOW MEASUREMENT WITH PULSED DOPPLER FLOWMETER IN CONSCIOUS RAT [J].
HAYWOOD, JR ;
SHAFFER, RA ;
FASTENOW, C ;
FINK, GD ;
BRODY, MJ .
AMERICAN JOURNAL OF PHYSIOLOGY, 1981, 241 (02) :H273-H278
[5]   THE HUMAN ENDOTHELIN FAMILY - 3 STRUCTURALLY AND PHARMACOLOGICALLY DISTINCT ISOPEPTIDES PREDICTED BY 3 SEPARATE GENES [J].
INOUE, A ;
YANAGISAWA, M ;
KIMURA, S ;
KASUYA, Y ;
MIYAUCHI, T ;
GOTO, K ;
MASAKI, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (08) :2863-2867
[6]  
LIPPTON HL, 1989, J VASC MED BIOL, V1, P184
[7]   BIOSYNTHESIS OF NITRIC-OXIDE FROM L-ARGININE - A PATHWAY FOR THE REGULATION OF CELL-FUNCTION AND COMMUNICATION [J].
MONCADA, S ;
PALMER, RMJ ;
HIGGS, EA .
BIOCHEMICAL PHARMACOLOGY, 1989, 38 (11) :1709-1715
[8]   NITRIC-OXIDE RELEASE ACCOUNTS FOR THE BIOLOGICAL-ACTIVITY OF ENDOTHELIUM-DERIVED RELAXING FACTOR [J].
PALMER, RMJ ;
FERRIGE, AG ;
MONCADA, S .
NATURE, 1987, 327 (6122) :524-526
[9]   MOLECULAR MECHANISM OF ACTION OF THE VASOCONSTRICTOR PEPTIDE ENDOTHELIN [J].
VANRENTERGHEM, C ;
VIGNE, P ;
BARHANIN, J ;
SCHMIDALLIANA, A ;
FRELIN, C ;
LAZDUNSKI, M .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 157 (03) :977-985
[10]   REGIONAL VASODILATION IS A PROMINENT FEATURE OF THE HEMODYNAMIC-RESPONSE TO ENDOTHELIN IN ANESTHETIZED, SPONTANEOUSLY HYPERTENSIVE RATS [J].
WRIGHT, CE ;
FOZARD, JR .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 155 (1-2) :201-203