Epidermal Graft Accelerates the Healing of Acute Wound: A Self-controlled Case Report

被引:3
作者
Bystrzonowski, Nicola [1 ]
Hachach-Haram, Nadine [1 ]
Kanapathy, Muholan [1 ,2 ]
Richards, Toby [1 ,2 ]
Mosahebi, Afshin [1 ,2 ]
机构
[1] Royal Free London Hosp, Dept Plast & Reconstruct Surg, Royal Free Hosp, Wound Healing Grp, London, England
[2] Royal Free Hosp, Dept Plast & Reconstruct Surg, Wound Healing Grp, London, England
关键词
D O I
10.1097/GOX.0000000000001119
中图分类号
R61 [外科手术学];
学科分类号
摘要
Wound care represents a significant socioeconomic burden, with over half of chronic wounds taking up to a year to heal. Measures to accelerate wound healing are beneficial to patients and also reduce the cost and burden of wound management. Epidermal grafting (EG) is an emerging option for autologous skin grafting in the outpatient setting to improve wound healing. Although several case series have previously reported good clinical outcome with EG, the healing rate in comparison to conservative wound management is not known. In this report, we compare the weekly healing rate of 2 separate wounds in the same patient, one treated with EG and the other with dressings. The treated wound showed accelerated healing, with the healing rate being the highest at the first 2 weeks after EG. The average healing time of the treated wound was 40% faster compared with the control wound. EG accelerates healing of acute wounds, potentially reducing the healthcare cost and surgical burden.
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页数:4
相关论文
共 10 条
[1]  
Brigham Peter A., 1996, Journal of Burn Care and Rehabilitation, V17, P95, DOI 10.1097/00004630-199603000-00003
[2]  
Gabriel Allen, 2014, Surg Technol Int, V25, P55
[3]   Health economic burden that different wound types impose on the UK's National Health Service [J].
Guest, Julian F. ;
Ayoub, Nadia ;
McIlwraith, Tracey ;
Uchegbu, Ijeoma ;
Gerrish, Alyson ;
Weidlich, Diana ;
Vowden, Kathryn ;
Vowden, Peter .
INTERNATIONAL WOUND JOURNAL, 2017, 14 (02) :322-330
[4]   A prospective, multicentre study on the use of epidermal grafts to optimise outpatient wound management [J].
Hachach-Haram, Nadine ;
Bystrzonowski, Nicola ;
Kanapathy, Muholan ;
Smith, Oliver ;
Harding, Keith ;
Mosahebi, Ash ;
Richards, Toby .
INTERNATIONAL WOUND JOURNAL, 2017, 14 (01) :241-249
[5]   The use of epidermal grafting for the management of acute wounds in the outpatient setting [J].
Hachach-Haram, Nadine ;
Bystrzonowski, Nicola ;
Kanapathy, Muholan ;
Edmondson, Sarah-Jayne ;
Twyman, Lucy ;
Richards, Toby ;
Mosahebi, Afshin .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2015, 68 (09) :1317-1318
[6]  
HENTZER B, 1975, ACTA DERM-VENEREOL, V55, P207
[7]   Epidermal grafting versus split-thickness skin grafting for wound healing (EPIGRAAFT): study protocol for a randomised controlled trial [J].
Kanapathy, Muholan ;
Hachach-Haram, Nadine ;
Bystrzonowski, Nicola ;
Harding, Keith ;
Mosahebi, Afshin ;
Richards, Toby .
TRIALS, 2016, 17
[8]  
Kirsner RS, 2015, WOUNDS, V27, P282
[9]   Epidermal Grafting Using a Novel Suction Blister-Harvesting System for the Treatment of Pyoderma Gangrenosum [J].
Richmond, Nicholas A. ;
Lamel, Sonia A. ;
Braun, Liza R. ;
Vivas, Alejandra C. ;
Serena, Thomas ;
Kirsner, Robert S. .
JAMA DERMATOLOGY, 2014, 150 (09) :999-1000
[10]   Use of a Novel Epidermal Harvesting System in Resource-Poor Countries [J].
Serena, Thomas ;
Francius, Adler ;
Taylor, Cristin ;
MacDonald, John .
ADVANCES IN SKIN & WOUND CARE, 2015, 28 (03) :107-112