EFFECT OF SYNTHETIC ANALOGS OF DERMORPHIN ON MITOSIS IN THE CORNEAL AND LINGUAL EPITHELIUM OF ALBINO-RATS

被引：0

作者：

FLEISHMAN, MY ^{[1
]}

RADIVOZ, MI ^{[1
]}

TIMOSHIN, S ^{[1
]}

YAROVA, EP ^{[1
]}

KESELMAN, SA ^{[1
]}

机构：

[1] MED INST,CENT RES LAB,KHABAROVSK,RUSSIA

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1994年 / 118卷 / 11期

关键词：

DEMORPHIN; DNA SYNTHESIS; MITOSIS;

D O I：

10.1007/BF02444626

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A study of the effects of synthetic analogs of dermorphin which are prime agonists of the mu-opiate receptors, on cell division in the corneal and lingual epithelium of albino rats showed that both analogs depressed DNA synthesis in the corneal and lingual epithelium 4 h after administration. In the lingual epithelium DNA synthesis and the mitogenic index were still depressed 24 h after drug administration. In the cornea cell division parameters had normalized by this time.

引用

页码：1205 / 1207

页数：3