EFFECT OF BECLOMETHASONE DIPROPIONATE NASAL AEROSOL ON SERUM MARKERS OF BONE METABOLISM IN CHILDREN WITH SEASONAL ALLERGIC RHINITIS

被引：13
作者：
MARTINATI, LC
SETTE, L
CHIOCCA, E
ZANINOTTO, M
PLEBANI, M
BONER, AL
机构：
[1] UNIV VERONA,DEPT PEDIAT,VERONA,ITALY
[2] UNIV PADUA,INST LAB MED,PADUA,ITALY
来源：
CLINICAL AND EXPERIMENTAL ALLERGY | 1993年 / 23卷 / 12期
关键词：
D O I：
10.1111/j.1365-2222.1993.tb00288.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Thirty-nine children with grass pollen hay fever were randomly treated with nasal inhaled beclomethasone dipropionate (BDP) 200 or 400 mu g/day or sodium cromoglycate (SCG) 30 mg/day for 2 months during the pollen season. Serum osteocalcin (OC), parathyroid hormone (PTH), fetal alkaline phosphatase (AP), bone alkaline phosphatase (BAP) and type I collagen telopeptide (ICTP) were measured immediately before, 1 and 2 months after treatment and 1 week after stopping the therapy. No significant changes in OC, PTH, AP, BAP and ICTP serum level occurred within each group. Minor and probably clinically insignificant between group differences were occasionally found. Our study shows that BDP nasal spray has no significant effect on common markers of bone metabolism.
引用
收藏
页码：986 / 991
页数：6
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