INTERFERON-ASSOCIATED RETINOPATHY

被引：231

作者：

GUYER, DR

TIEDEMAN, J

YANNUZZI, LA

SLAKTER, JS

PARKE, D

KELLEY, J

TANG, RA

MARMOR, M

ABRAMS, G

MILLER, JW

GRAGOUDAS, ES

机构：

[1] DUKE UNIV,CTR EYE,DURHAM,NC 27706

[2] UNIV OKLAHOMA,DEPT OPHTHALMOL,OKLAHOMA CITY,OK

[3] GREATER BALTIMORE MD MED CTR,DEPT OPHTHALMOL,BALTIMORE,MD

[4] UNIV TEXAS,SCH MED,DEPT OPHTHALMOL,HOUSTON,TX 77025

[5] STANFORD UNIV,DEPT OPHTHALMOL,PALO ALTO,CA 94304

[6] MED COLL WISCONSIN,DEPT OPHTHALMOL,MILWAUKEE,WI 53226

[7] HARVARD UNIV,MASSACHUSETTS EYE & EAR INFIRM,SCH MED,RETINA SERV,BOSTON,MA 02114

来源：

ARCHIVES OF OPHTHALMOLOGY | 1993年 / 111卷 / 03期

关键词：

D O I：

10.1001/archopht.1993.01090030068041

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Interferon alfa is used to treat various systemic disorders and recently has been suggested as a possible treatment for choroidal neovascularization. We report 10 cases of retinal ischemia associated with the use of interferon alfa for various illnesses. The retinal findings include cotton-wool spot formation, capillary nonperfusion, arteriolar occlusion, and hemorrhage. The retinal complications may sometimes be reversible when treatment is stopped. Our findings emphasize the need to have patients who are receiving interferon alfa therapy monitored for these retinal complications, which may rarely be associated with permanent loss of vision secondary to closure of retinal capillaries.

引用

页码：350 / 356

页数：7

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