MAGNETIC BEAD CAPTURE OF EXPRESSED SEQUENCES ENCODED WITHIN LARGE GENOMIC SEGMENTS

被引：83

作者：

TAGLE, DA

SWAROOP, M

LOVETT, M

COLLINS, FS

机构：

[1] UNIV MICHIGAN,MED CTR,DEPT INTERNAL MED,ANN ARBOR,MI 48109

[2] UNIV TEXAS,SW MED CTR,DEPT BIOCHEM,DALLAS,TX 75235

来源：

NATURE | 1993年 / 361卷 / 6414期

关键词：

D O I：

10.1038/361751a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Magnetic bead capture utilizes blotln-streptavidin magnetic bead technology to Isolate cDNAs rapidly from large genomic Intervals, giving several thousand-fold enrichment of the selected cDNAs. The technique can allow parallel analysis of several large genomic segments of varying complexities and can be applied to the isolation of expressed sequences from various tissue sources.

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页码：751 / 753

页数：3

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