THRESHOLD RESPONSES IN FORMALDEHYDE-SENSITIVE SUBJECTS

被引:82
作者
JORDAN, WP
SHERMAN, WT
KING, SE
机构
[1] Richmond, Virginia
关键词
D O I
10.1016/S0190-9622(79)70003-X
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Patch tests with three low concentrations of formaldehyde were applied continuously in formaldehyde-sensitive subjects for 1 wk. The closed patch test method produced a response to 30 parts per million (ppm) in some subjects by 120 continuous hours of testing. Thirteen subjects then sprayed a 30-ppm formaldehyde solution in an axilla on a double-blind, controlled, 2-wk-use test. Their responses to 30 ppm aqueous formaldehyde indicate that levels below this concentration should be tolerated by sensitive subjects if repeatedly applied to normal skin. Popular formaldehyde-releasing preservatives can be above or below this threshold-eliciting response. © 1979, American Academy of Dermatology, Inc.. All rights reserved.
引用
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页码:44 / 48
页数:5
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