DESTRUCTION OF CYTOCHROME-P-450 BY ALLYLISOPROPYLACETAMIDE IS A SUICIDAL PROCESS

被引：87
作者：
DEMONTELLANO, PRO [1 ]
MICO, BA [1 ]
机构：
[1] UNIV CALIF SAN FRANCISCO, CTR LIVER, SAN FRANCISCO, CA 94143 USA
来源：
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1981年 / 206卷 / 01期
关键词：
D O I：
10.1016/0003-9861(81)90063-1
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：43 / 50
页数：8
相关论文
共 38 条
[1]   DECREASED LEVELS OF CYTOCHROME-P-450 AND CATALASE IN HEPATIC PORPHYRIA CAUSED BY SUBSTITUTED ACETAMIDES AND BARBITURATES - IMPORTANCE OF ALLYL GROUP IN MOLECULE OF ACTIVE DRUGS [J].
ABBRITTI, G ;
DEMATTEI.F .
CHEMICO-BIOLOGICAL INTERACTIONS, 1972, 4 (04) :281-&
[2]   SUICIDE ENZYME INACTIVATORS [J].
ABELES, RH ;
MAYCOCK, AL .
ACCOUNTS OF CHEMICAL RESEARCH, 1976, 9 (09) :313-319
[3]   DEGRADATION OF DIFFERENT FORMS OF CYTOCHROME-P-450 INVIVO BY FLUROXENE AND ALLYL-ISO-PROPYLACETAMIDE [J].
BRADSHAW, JJ ;
ZIMAN, MR ;
IVANETICH, KM .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 85 (03) :859-866
[4]  
BRINKSCHULTEFREITAS M, 1979, ARCH TOXICOL, V42, P137
[5]  
CORREIA MA, 1973, DRUG METAB DISPOS, V1, P139
[6]  
CORREIA MA, 1979, J BIOL CHEM, V254, P15
[7]  
De Matteis F, 1971, Biochem J, V124, P767
[8]  
DEMATTEIS F, 1978, HDB EXPT PHARMACOLOG, V44, P129
[9]  
DEMONTELLANO PRO, 1979, ARCH BIOCHEM BIOPHYS, V197, P524
[10]  
DEMONTELLANO PRO, 1978, BIOCHEM BIOPH RES CO, V83, P132
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