SECOND DEGREE ATRIOVENTRICULAR BLOCK, WENCKEBACH TYPE, TRIGGERED BY MEFLOQUINE

被引：0

作者：

Figueroa, Jorge A. ^{[1
]}

Serra, Jose L. ^{[1
]}

Cooke, Roberto ^{[1
]}

Daghero, Fernando ^{[1
]}

机构：

[1] Unidad Cardiovasc, Hipolito Irigoyen 384, RA-5000 Cordoba, Argentina

来源：

REVISTA DE LA FEDERACION ARGENTINA DE CARDIOLOGIA | 2009年 / 38卷 / 04期

关键词：

Mefloquine; Atrioventricular block; Cardiotoxicity;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Mefloquine is a drug used in the prophylaxis and in the treatment of malaria. It is infrequently related to relevant cardiovascular adverse events. Among them, alterations in the atrioventricular conduction have been described. We present a male patient, aged 26, who consulted for asthenia, general discomfort and palpitations in the context of antimalarial prophylaxis with mefloquine during a journey in an endemic area. The patient did not present any relevant medical antecedent. A second degree atrioventricular block, Wenckebach type, was confirmed by electrocardiography. Studies were done ruling out other probably etiologies. Treatment of support was done recovering gradually a normal atrioventricular conduction after the drug was discontinued. A brief review of the etio-pathogenic relationship between mefloquina and atrioventricular conduction disturbances is presented.

引用

页码：216 / 219

页数：4

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