SYNTHESIS OF THE TRICYCLIC NUCLEUS OF THE ALKALOID STEMOFOLINE - X-RAY CRYSTAL-STRUCTURE OF (4RS,5RS,7SR,10RS)-10-BUTYL-5-HYDROXY-1-AZATRICYCLO[5.3.0.0(4,10)]DECAN-2-ONE

被引：34

作者：

BEDDOES, RL ^{[1
]}

DAVIES, MPH ^{[1
]}

THOMAS, EJ ^{[1
]}

机构：

[1] UNIV MANCHESTER,DEPT CHEM,MANCHESTER M13 9PL,LANCS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 07期

关键词：

D O I：

10.1039/c39920000538

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The tricyclic lactams 20 and 21 have been synthesized using iminium ion cyclisations and formation of the third ring via halogen metal exchange; oxidation of the lactam 22 using lead(IV) acetate gave the tetracyclic ether 27 regioselectively.

引用

页码：538 / 540

页数：3

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