IMMOBILIZED ENZYMES AND IMMOBILIZED MICROBIAL-CELLS

Recently the enzyme industry has been developing rapidly, through advances in the biochemistry, bioorganic chemistry, and techniques of enzyme production by microorganisms. Many kinds of enzymes have been widely used in the fields of synthetic chemical, food, and medical industries. However, these enzymes have been conventionally used in soluble form, which has some disadvantages. Thus, the immobilization of enzymes has been the subject of increased intrest, and a number of papers on potential applications of immobilized enzymes have been published. Further, very recently many papers have been published on the immobilized microbial cells for the purpose of transformations of organic compounds. In this paper, the preparations, the enzymatic properties and the utilizations of these immobilized systems are reviewed. © 1978, The Society of Synthetic Organic Chemistry, Japan. All rights reserved.