USE OF SITE-DIRECTED MUTAGENESIS TO INVESTIGATE THE BASIS FOR THE SPECIFICITY OF HIRUDIN

被引：175

作者：

BRAUN, PJ ^{[1
]}

DENNIS, S ^{[1
]}

HOFSTEENGE, J ^{[1
]}

STONE, SR ^{[1
]}

机构：

[1] FRIEDRICH MIESCHER INST,POB 2543,CH-4002 BASEL,SWITZERLAND

来源：

BIOCHEMISTRY | 1988年 / 27卷 / 17期

关键词：

D O I：

10.1021/bi00417a048

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：6517 / 6522

页数：6

相关论文

共 46 条

[1] BAGDY O, 1976, METHOD ENZYMOL, V45, P669
[2] THE CYSTATINS - A NEW CLASS OF PEPTIDASE INHIBITORS
BARRETT, AJ
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1987, 12 (05) : 193 - 196
[3] PHYSICAL EVIDENCE FOR AN APOLAR BINDING-SITE NEAR CATALYTIC CENTER OF HUMAN ALPHA-THROMBIN
BERLINER, LJ
SHEN, YYL
[J]. BIOCHEMISTRY, 1977, 16 (21) : 4622 - 4626
[4] BLOMBACK JG, 1977, CHEM BIOL THROMBIN, P275
[5] ALPHA-1-ANTITRYPSIN AND THE SERPINS - VARIATION AND COUNTERVARIATION
CARRELL, R
TRAVIS, J
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1985, 10 (01) : 20 - 24
[6] THE FUNCTIONAL DOMAIN OF HIRUDIN, A THROMBIN-SPECIFIC INHIBITOR
CHANG, JY
[J]. FEBS LETTERS, 1983, 164 (02) : 307 - 313
[7] CLAESON G, 1977, NEW METHODS ANAL COA, P37
[8] THE CONFORMATIONS OF HIRUDIN IN SOLUTION - A STUDY USING NUCLEAR-MAGNETIC-RESONANCE, DISTANCE GEOMETRY AND RESTRAINED MOLECULAR-DYNAMICS
CLORE, GM
SUKUMARAN, DK
NILGES, M
ZARBOCK, J
GRONENBORN, AM
[J]. EMBO JOURNAL, 1987, 6 (02) : 529 - 537
[9] ISOLATION AND CHARACTERIZATION OF HIRUDIN ISOINHIBITORS AND SEQUENCE-ANALYSIS OF HIRUDIN-PA
DODT, J
MACHLEIDT, W
SEEMULLER, U
MASCHLER, R
FRITZ, H
[J]. BIOLOGICAL CHEMISTRY HOPPE-SEYLER, 1986, 367 (08): : 803 - 811
[10] THE COMPLETE AMINO-ACID-SEQUENCE OF HIRUDIN, A THROMBIN SPECIFIC INHIBITOR - APPLICATION OF COLOR CARBOXYMETHYLATION
DODT, J
MULLER, HP
SEEMULLER, U
CHANG, JY
[J]. FEBS LETTERS, 1984, 165 (02) : 180 - 184

← 1 2 3 4 5 →