A SHORT APPROACH TO FUNCTIONALIZED HOMOCHIRAL PIPERIDINONES

被引：33

作者：

HERMITAGE, SA ^{[1
]}

MOLONEY, MG ^{[1
]}

机构：

[1] UNIV OXFORD,DYSON PERRINS LAB,OXFORD OX1 3QY,ENGLAND

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 08期

关键词：

D O I：

10.1016/0957-4166(94)80113-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The preparation of homochiral lactam 4 in 5 steps from (S)-lysine is described. Conversion to bicyclic O,N-acetal 5 provides a useful template for further elaboration to highly substituted piperidinones with excellent diastereoselectivity.

引用

页码：1463 / 1464

页数：2

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