MODEL OF AN EXTRACELLULAR ELECTRIC-FIELD OF A NEURON

被引：0
作者：
DVORAK, I
机构：
[1] Institute of Physiology, Czechoslovak Academy of Sciences, Prague
来源：
KYBERNETES | 1979年 / 8卷 / 01期
关键词：
D O I：
10.1108/eb005505
中图分类号：
TP3 [计算技术、计算机技术];
学科分类号：
0812 ;
摘要：
A mathematical model of the extracellular electric field of an active neuron is proposed under a set of simplifying assumptions. The basic assumption is that the electric field is quasi-stationary. Consequently, the field potential can be obtained by solving the Laplace equation. The main aim of the model is to formulate boundary conditions, which are not rotationally symmetric, and to include the influence of dendrites in the computations. A formula representing the electrical and geometrical composition of the nerve cell is developed, which describes the time and space behavior of the extracellular potential. The results obtained from the model and experimental data closely agree. Possible applications of the model as a means of interpreting experimental data are discussed. © 1979, MCB UP Limited. All rights reserved.
引用
收藏
页码：51 / 58
页数：8
相关论文
共 37 条
[1]  
Huxley A.P., Hodgkin A.L., A quantitative description of membrane current and its application to conduction and excitation in nerve, J. Physiol., 117, (1952)
[2]  
Fulton J.Q., Physiology of the Nervous System, (1951)
[3]  
Tasaki I., Provedenije Nervnogo Impulsa, (1957)
[4]  
Coombs J.S., Curtis R.D., Eccles J.C., The interpretation of spike potentials of motoneurones, J. Physiol., 139, (1957)
[5]  
Coombs J.S., Curtis R.D., Eccles J.C., The generation of impulses in motoneurones, J. Physiol., 139, (1957)
[6]  
Eccles J.C., Fiziologija Nervnych Kletok, (1959)
[7]  
Eccles J.C., Fiziologija Sinapsov, (1966)
[8]  
Eccles J.C., The excitatory responses of spinal neurons, 12, (1967)
[9]  
Rall W., Electrophysiology of a dendritic neuron model, Biophys. J., 2, (1962)
[10]  
Rall W., Time constants and electrotonic length of membrane cylinders and neurons, Biophys. J., 9, (1969)
1234