EFFECT OF ORGANIC PHOSPHORUS COMPOUNDS AND ALKYLATING AGENTS ON RAT FETUS

被引：61
作者：
KIMBROUGH, RD
GAINES, TB
机构：
[1] Department, of Health Education and Welfare, Toxicology Laboratory, Atlanta, 30333, National Communicable Disease Center, Bureau of Disease Prevention and Environmental Control, Public Health Service
来源：
ARCHIVES OF ENVIRONMENTAL HEALTH | 1968年 / 16卷 / 06期
关键词：
D O I：
10.1080/00039896.1968.10665156
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The effects of parathion, dichlorvos, diazinon, malathion, apholate, and tepa on the rat fetus were studied when the material was given intraperitoneally. At levels producing toxic symptoms in the dams, parathion, dichlorvos, diazinon, apholate, and tepa were found to affect the fetus either by causing malformations, resorptions, or reducing the weight of the fetus and placenta. Malathion at toxic dosage levels neither affected the weight of the fetus nor produced malformations. At dosage levels which were tolerated by the dams, parathion, diazinon, and tepa caused a great number of resorptions. The incidence of resorptions was not higher than that of the controls in rats that had been given dichlorvos, malathion, or apholate. © 1968 Taylor & Francis Group, LLC.
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页码：805 / +
页数：1
相关论文
共 10 条
[1]  
GAINES TB, 1966, B WORLD HEALTH ORGAN, V34, P317
[2]  
GHADIRI M, 1967, TOXICOL APPL PHARM, V10, P392
[3]  
GHADIRI M, 1965, TOXICOL APPL PHARM, V7, P484
[4]  
MARLIAC GP, 1964, FED PROC, V23, P105
[5]  
MURPHY ML, TERATOLOGY PRINCIPLE, P145
[6]  
WILSON JG, TERATOLOGY PRINCI ED, P145
[7]  
WILSON JG, TERATOLOGY PRINCIPLE, P251
[8]  
WILSON JG, TERATOLOGY PRINCI ED, P251
[9]  
Wulff LMR, 1935, P SOC EXP BIOL MED, V32, P678, DOI 10.3181/00379727-32-7815C
[10]  
YOUNGER RL, 1965, AM J VET RES, V26, P991
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