HUMAN INTESTINE EPITHELIAL-CELL ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE

被引:0
作者
SINE, JP
FERRAND, R
CLOAREC, D
LEHUR, PA
COLAS, B
机构
[1] CTR RECH BIOL PHYSICOCHIM CELLULAIRES,BIOCHIM LAB 2,2 RUE HOUSSINIERE,F-44072 NANTES 03,FRANCE
[2] UNIV NANTES,CHU NORD,BIOL DEV LAB,F-44072 NANTES 03,FRANCE
[3] UNIV NANTES,CHU NORD,SERV GASTROENTEROL,F-44072 NANTES 03,FRANCE
关键词
CHOLINESTERASES; ACETYLCHOLINESTERASE; BUTYRYLCHOLINESTERASE; EPITHELIAL CELL; HUMAN INTESTINE;
D O I
暂无
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The epithelial cells of the human intestine exhibit a cholinesterase activity which is restricted to the apex of the villi. This activity displays a maximum in the colon and a minimum in the jejunum. Contrary to most of the studied vertebrates, the human cells present both acetylcholinesterase and butyrylcholinesterase activities, acetylcholinesterase being predominant in all the intestinal segments: duodenum, jejunum, ileum and colon. Like in the other vertebrates, only globular forms are identified by sucrose gradient centrifugation. However, the simultaneous presence, on the one hand of three globular forms (G1, G2 and G4) and, on the other hand of soluble as well as detergent-soluble molecular species seems to be a particular feature of the human cells.
引用
收藏
页码:145 / 149
页数:5
相关论文
共 50 条
[41]   Comparing the effects of organic cosolvents on acetylcholinesterase and butyrylcholinesterase activity [J].
Novales, Noelle A. ;
Schwans, Jason P. .
ANALYTICAL BIOCHEMISTRY, 2022, 654
[42]   Electrochemical Biosensors based on Acetylcholinesterase and Butyrylcholinesterase. A Review [J].
Pohanka, Miroslav .
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2016, 11 (09) :7440-7452
[43]   Examination of cross-antigenicity of acetylcholinesterase and butyrylcholinesterase using anti-acetylcholinesterase antibodies [J].
George, KM ;
Montgomery, MA ;
Sandoval, LE ;
Thompson, CM .
TOXICOLOGY LETTERS, 2002, 126 (02) :99-105
[44]   Synthesis of Imperatorin Analogs and Their Evaluation as Acetylcholinesterase and Butyrylcholinesterase Inhibitors [J].
Granica, Sebastian ;
Kiss, Anna K. ;
Jaronczyk, Malgorzata ;
Maurin, Jan K. ;
Mazurek, Aleksander P. ;
Czarnocki, Zbigniew .
ARCHIV DER PHARMAZIE, 2013, 346 (11) :775-782
[45]   Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase [J].
Jonczyk, Jakub ;
Kukulowicz, Jedrzej ;
Latka, Kamil ;
Malawska, Barbara ;
Jung, Young-Sik ;
Musilek, Kamil ;
Bajda, Marek .
BIOMOLECULES, 2021, 11 (02) :1-21
[46]   Calcium-activated butyrylcholinesterase in human skin protects acetylcholinesterase against suicide inhibition by neurotoxic organophosphates [J].
Schallreuter, Karin U. ;
Gibbons, Nicholas C. J. ;
Elwary, Souna M. ;
Parkin, Susan M. ;
Wood, John M. .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2007, 355 (04) :1069-1074
[47]   Purification of recombinant human butyrylcholinesterase on Hupresin® [J].
Lockridge, Oksana ;
David, Emilie ;
Schopfer, Lawrence M. ;
Masson, Patrick ;
Brazzolotto, Xavier ;
Nachon, Florian .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2018, 1102 :109-115
[48]   Butyrylcholinesterase and acetylcholinesterase activity and quantal transmitter release at normal and acetylcholinesterase knockout mouse neuromuscular junctions [J].
Minic, J ;
Chatonnet, A ;
Krejci, E ;
Molgó, J .
BRITISH JOURNAL OF PHARMACOLOGY, 2003, 138 (01) :177-187
[49]   Different Effects of Forsythoside E on Acetylcholinesterase and Butyrylcholinesterase by Fluorescent Spectroscopy [J].
Ch. Gao ;
H. Du .
Journal of Applied Spectroscopy, 2022, 89 :559-566
[50]   Kinetics and mechanisms of acetylcholinesterase and butyrylcholinesterase inhibition by cardiovascular drugs and, benzodiazepines [J].
Chiou, SY ;
Lai, GW ;
Tsai, YH ;
Lee, YR ;
Lin, LY ;
Lin, GL .
JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2005, 52 (04) :843-848