THE ONTOGENY OF BRONCHIAL REACTIVITY

被引：0

作者：

FAYON, M ^{[1
]}

BENJEBRIA, A ^{[1
]}

ELLEAU, C ^{[1
]}

DEMARQUEZ, JL ^{[1
]}

MARTHAN, R ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,FAC MED VICTOR PACHON,PHYSIOL LAB,F-33076 BORDEAUX,FRANCE

来源：

ANNALES DE PEDIATRIE | 1995年 / 42卷 / 03期

关键词：

ONTOGENY; SMOOTH MUSCLE FIBER; BRONCHIAL HYPERREACTIVITY; NEONATE;

D O I：

暂无

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

This article reviews current knowledge on the mechanisms involved in the maturation of bronchial contractility in animal models and humans. Extrapolation of animal data to humans is risky. Results of an in vitro study in human neonates are reported. beta(2)-adrenoceptor agonists and cholinergic agents were effective in relieving early bronchospasm in mechanically-ventilated premature infants. Controlled studies are needed to determine whether these medications affect the subsequent occurrence of bronchial hyperreactivity in these patients.

引用

页码：170 / 175

页数：6

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