THE ONTOGENY OF BRONCHIAL REACTIVITY

被引:0
|
作者
FAYON, M [1 ]
BENJEBRIA, A [1 ]
ELLEAU, C [1 ]
DEMARQUEZ, JL [1 ]
MARTHAN, R [1 ]
机构
[1] UNIV BORDEAUX 2,FAC MED VICTOR PACHON,PHYSIOL LAB,F-33076 BORDEAUX,FRANCE
来源
ANNALES DE PEDIATRIE | 1995年 / 42卷 / 03期
关键词
ONTOGENY; SMOOTH MUSCLE FIBER; BRONCHIAL HYPERREACTIVITY; NEONATE;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This article reviews current knowledge on the mechanisms involved in the maturation of bronchial contractility in animal models and humans. Extrapolation of animal data to humans is risky. Results of an in vitro study in human neonates are reported. beta(2)-adrenoceptor agonists and cholinergic agents were effective in relieving early bronchospasm in mechanically-ventilated premature infants. Controlled studies are needed to determine whether these medications affect the subsequent occurrence of bronchial hyperreactivity in these patients.
引用
收藏
页码:170 / 175
页数:6
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