ASSOCIATION OF AGE WITH REGIONAL CEREBRAL OXYGEN UTILIZATION - A POSITRON EMISSION TOMOGRAPHY STUDY

被引:20
作者
BURNS, A [1 ]
TYRRELL, P [1 ]
机构
[1] HAMMERSMITH HOSP,MRC,CYCLOTRON UNIT,LONDON W12 0HS,ENGLAND
关键词
D O I
10.1093/ageing/21.5.316
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Positron emission tomography scans were performed on 14 normal subjects over the age of 50. Cerebral metabolic rate for oxygen (CMRO2) was assessed in a number of cortical and subcortical regions. There was a trend for a decrease in CMRO2 with age but this was significant only in the parietal lobe. There was a suggestion that the age/CMRO2 correlation became less strong with advancing age. CMRO2 in the occipital lobe, subcortical regions and cerebellum was not related to age. The relationship between CMRO2 and age is discussed.
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页码:316 / 320
页数:5
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