COCKROACH ALLERGENIC ACTIVITY - ANALYSIS OF COMMERCIAL COCKROACH AND DUST EXTRACTS

被引：16

作者：

LEHRER, SB ^{[1
]}

HORNER, WE ^{[1
]}

MENON, PK ^{[1
]}

OLIVER, J ^{[1
]}

HAUCK, P ^{[1
]}

机构：

[1] CTR LABS, PORT WASHINGTON, NY USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 1991年 / 88卷 / 06期

关键词：

COCKROACH; ALLERGENS; COMMERCIAL EXTRACTS; DUST; SKIN TEST; RAST;

D O I：

10.1016/0091-6749(91)90246-K

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Previous investigations demonstrated that cockroach whole bodies and feces are important sources of allergens in the induction/exacerbation of bronchial asthma. The current study investigated different cockroach source materials, commercial extracts, and house dust extracts for cockroach allergenic activity. In general, extracts from four different sources of either American or German cockroaches contained similar amounts of allergenic activity by RAST inhibition. Three commercial American cockroach extracts compared by RAST inhibition had similar allergenic activity on an equal protein basis. Skin test results correlated house dust reactivity to both commercial and inhouse cockroach wholebody extracts and to fecal extracts. Six different samples of house dust obtained from vacuum cleaners in the New Orleans area and three commercially obtained house dust extracts contained varying quantities of cockroach allergenic activity by RAST inhibition. These studies demonstrate that commercial cockroach extracts vary in allergenic activity and that all house dust extracts tested contain cockroach allergens.

引用

页码：895 / 901

页数：7

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