THE TORSO PATHWAY IN DROSOPHILA - LESSONS ON RECEPTOR TYROSINE KINASE SIGNALING AND PATTERN-FORMATION

被引：99
作者：
DUFFY, JB
PERRIMON, N
机构：
[1] Department of Genetics, Harvard Medical School, Boston
[2] Howard Hughes Medical Institute, Harvard Medical School, Boston
来源：
DEVELOPMENTAL BIOLOGY | 1994年 / 166卷 / 02期
关键词：
D O I：
10.1006/dbio.1994.1324
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Pattern formation at the anterior and posterior termini of the Drosophila embryo involves intercellular communication via the Torso receptor tyrosine kinase (RTK). Recent advances in the understanding of Torso signaling has provided further support for the conservation of a signal transduction cassette downstream of RTKs. In addition, the analysis of the Torso pathway has begun to reveal general molecular mechanisms by which cells may impart patterning information to their neighbors through the use of RTKs. (C) 1994 Academic Press, Inc.
引用
收藏
页码：380 / 395
页数：16
相关论文
共 88 条
[1]  
AMBROSIO L, 1989, DEVELOPMENT, V106, P145
[2]   REQUIREMENT OF THE DROSOPHILA RAF HOMOLOG FOR TORSO FUNCTION [J].
AMBROSIO, L ;
MAHOWALD, AP ;
PERRIMON, N .
NATURE, 1989, 342 (6247) :288-291
[3]   RAF-1 IS A POTENTIAL SUBSTRATE FOR MITOGEN-ACTIVATED PROTEIN-KINASE INVIVO [J].
ANDERSON, NG ;
PING, LI ;
MARSDEN, LA ;
WILLIAMS, N ;
ROBERTS, TM ;
STURGILL, TW .
BIOCHEMICAL JOURNAL, 1991, 277 :573-576
[4]   PRIMARY STRUCTURE, EXPRESSION, AND SIGNAL-DEPENDENT TYROSINE PHOSPHORYLATION OF A DROSOPHILA HOMOLOG OF EXTRACELLULAR SIGNAL-REGULATED KINASE [J].
BIGGS, WH ;
ZIPURSKY, SL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (14) :6295-6299
[5]   THE DROSOPHILA ROLLED LOCUS ENCODES A MAP KINASE REQUIRED IN THE SEVENLESS SIGNAL-TRANSDUCTION PATHWAY [J].
BIGGS, WH ;
ZAVITZ, KH ;
DICKSON, B ;
VANDERSTRATEN, A ;
BRUNNER, D ;
HAFEN, E ;
ZIPURSKY, SL .
EMBO JOURNAL, 1994, 13 (07) :1628-1635
[6]  
BOLLAG G, 1991, ANNU REV CELL BIOL, V7, P601, DOI 10.1146/annurev.cellbio.7.1.601
[7]   THE SON OF SEVENLESS GENE-PRODUCT - A PUTATIVE ACTIVATOR OF RAS [J].
BONFINI, L ;
KARLOVICH, CA ;
DASGUPTA, C ;
BANERJEE, U .
SCIENCE, 1992, 255 (5044) :603-606
[8]   RAF ACTS DOWNSTREAM OF THE EGF RECEPTOR TO DETERMINE DORSOVENTRAL POLARITY DURING DROSOPHILA OOGENESIS [J].
BRAND, AH ;
PERRIMON, N .
GENES & DEVELOPMENT, 1994, 8 (05) :629-639
[9]   CONTROL AND FUNCTION OF TERMINAL GAP GENE ACTIVITY IN THE POSTERIOR POLE REGION OF THE DROSOPHILA EMBRYO [J].
BRONNER, G ;
JACKLE, H .
MECHANISMS OF DEVELOPMENT, 1991, 35 (03) :205-211
[10]   SERUM-INDUCED, TPA-INDUCED, AND RAS-INDUCED EXPRESSION FROM AP-1/ETS-DRIVEN PROMOTERS REQUIRES RAF-1 KINASE [J].
BRUDER, JT ;
HEIDECKER, G ;
RAPP, UR .
GENES & DEVELOPMENT, 1992, 6 (04) :545-556
123456789