EFFECT OF TERTIARY BASES ON O-BENZOTRIAZOLYLURONIUM SALT-INDUCED PEPTIDE SEGMENT COUPLING

被引：149

作者：

CARPINO, LA

EL-FAHAM, A

机构：

[1] Department of Chemistry, University of Massachusetts, Massachusetts 01003-4510, Box 34510, Amherst

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 04期

关键词：

D O I：

10.1021/jo00083a001

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Collidine activation of O-(7-azabenzotriazolyl)-uronium salts leads to relatively low levels of racemization in the coupling of peptide segments, especially with reagents derived from 1,1-carbonyldipyrrolidine.

引用

页码：695 / 698

页数：4

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