IMMUNOPATHOLOGY OF MOORENS ULCER

被引：64

作者：

FOSTER, CS

KENYON, KR

GREINER, J

GREINEDER, DK

FRIEDLAND, B

ALLANSMITH, MR

机构：

[1] UNIV FLORIDA, SCH MED, GAINESVILLE, FL 32611 USA

[2] HARVARD UNIV, SCH MED, DEPT OPHTHALMOL, BOSTON, MA 02115 USA

[3] MASSACHUSETTS EYE & EAR INFIRM, CORNEA SERV, BOSTON, MA 02114 USA

[4] ROBERT B BRIGHAM HOSP, DEPT MED, BOSTON, MA 02120 USA

来源：

AMERICAN JOURNAL OF OPHTHALMOLOGY | 1979年 / 88卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0002-9394(79)90459-8

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

In a 42-year-old man with bilateral severe Mooren's ulcers, results of immunologic studies were normal, with the exception of an in vitro blastogenic response of the patient's lymphocytes to corneal stroma. The histologic studies revealed vast numbers of vacuolated neutrophils with intracytoplasmic phagosomes in and about the ulcerating cornea. Although the progression of ulceration was initially unaltered by surgical and pharmacologic trials, systemic immuno-suppression with methotrexate may have prevented ulceration of the lamellar tectonic graft. © 1979.

引用

页码：149 / 159

页数：11

共 28 条

[1] MORPHOLOGICAL-CHANGES IN HUMAN CONJUNCTIVAL EPITHELIUM .1. NORMAL ELDERLY POPULATION [J].