EFFECT OF A MEMBRANE MODULATOR OF THE 3-HYDROXYPYRIDINE CLASS ON DEVELOPMENT OF PULMONARY-EDEMA

被引：0

作者：

MIKHAILOV, VP ^{[1
]}

SMIRNOV, LD ^{[1
]}

ZOLOTOV, NN ^{[1
]}

机构：

[1] KUPAVNA DRUG TECHNOL & SAFETY RES INST,KUPAVNA,USSR

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1990年 / 109卷 / 06期

关键词：

PULMONARY EDEMA; MEMBRANE MODULATORS; ANTIOXIDANTS;

D O I：

10.1007/BF00841436

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Lipid peroxidation (LPO) has been shown to proceed at an extremely low level in intact lungs. Reduction of antiradical activity of the lung tissue with enhancement of LPO is combined in some cases with the development of pulmonary edema (PE) [11]. Considering the marked damaging action of LPO products on cell membrane structures [6], it can be tentatively suggested that the use of active inhibitors of free-radical processes would be an effective means of prevention and treatment of PE.

引用

页码：753 / 755

页数：3

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