ASYMMETRIC CONSTRUCTION OF QUATERNARY CARBONS FROM CHIRAL MALONATES - TOTAL SYNTHESES OF (+)-EPILAURENE AND (-)-ISOLAURENE

被引：22

作者：

FADEL, A

CANET, JL

SALAUN, J

机构：

[1] Laboratoire des Carbocycles, associé au CNRS, Institut de Chimie Moléculaire d'Orsay

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 01期

关键词：

SESQUITERPENES; LAURENE; EPILAURENE; ISOLAURENE; RADICAL CYCLIZATION; WITTIG REACTION UNDER SONICATION; CHIRAL MALONIC ACID ESTER;

D O I：

10.1016/S0957-4166(00)86009-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Enantiomerically pure (+)-epilaurene and (-)-isolaurene were obtained from the chiral malonic acid ester (R)-(+)-4, via the 4-methyl-4-p-tolylhex-5-en-1-al (S)-9 prepared by double Wittig reaction under sonication, which underwent subsequent radical induced cyclization.

引用

页码：27 / 30

页数：4

共 22 条

[1] SYNTHETIC RADICAL CHEMISTRY - TOTAL SYNTHESIS OF (+/-)-ISOAMIJIOL [J].