ACETYLCHOLINE-RECEPTOR AND MYOGENIC FACTOR GENE-EXPRESSION IN TORPEDO EMBRYONIC-DEVELOPMENT

被引：5

作者：

ASHER, O

FUCHS, S

SOUROUJON, MC

机构：

[1] WEIZMANN INST SCI,DEPT CHEM IMMUNOL,IL-76100 REHOVOT,ISRAEL

[2] OPEN UNIV ISRAEL,IL-61392 TEL AVIV,ISRAEL

来源：

NEUROREPORT | 1994年 / 5卷 / 13期

关键词：

ACETYLCHOLINE RECEPTOR; TORPEDO; EMBRYONIC DEVELOPMENT; GENE EXPRESSION; MYOGENIC FACTORS; MYOD; MRF4; ELECTRIC ORGAN; MUSCLE;

D O I：

10.1097/00001756-199408150-00010

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

THE mRNA levels of acetylcholine receptor (AChR) and myogenic factors were followed during embryonic development of Torpedo skeletal muscle and its homologue, the electric organ. A different developmental pattern of AChR gene expression was found in these two tissues: a slight decrease in the muscle, and a marked increase, concomitant with synapse formation, in the electric organ. However, the developmental pattern of MyoD and MRF4 mRNA levels was similar in both tissues, with no significant changes during development. This is in contrast with the sharp increase in the expression of AChR in the electric organ and may suggest that the burst in the expression of AChR during the differentiation of myotubes into electrocytes is not regulated by changes in the myogenic factor mRNA levels.

引用

页码：1581 / 1584

页数：4

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