CONTROL OF THE INITIATION OF DNA-REPLICATION IN ESCHERICHIA-COLI .2. FUNCTION OF THE DNAA PRODUCT

被引：15

作者：

ZAHN, G ^{[1
]}

MESSER, W ^{[1
]}

机构：

[1] MAX PLANCK INST MOLEC GENET,TRAUTNER ABT,IHNESTR 63-73,D-1000 BERLIN 33,FED REP GER

来源：

MOLECULAR & GENERAL GENETICS | 1979年 / 168卷 / 02期

关键词：

D O I：

10.1007/BF00431445

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

General growth parameters and the kinetics of DNA replication have been determined in merogenotes carrying different combinations of the dnaA+ and the dnaA5 allele. The strain which is homozygous diploid for dnaA5 is different from all other combinations in cell volume, DNA per mass ratio, number of replication points per chromosome, and polymerization rate of DNA. From this we deduce that the dnaA product is a positively acting regulatory protein in initiation. In an appendix we show that in combinations between the dnaA5 and dnaA204 alleles the phenotype of dnaA5 is dominant. © 1979 Springer-Verlag.

引用

页码：197 / 209

页数：13

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