INACTIVE RENIN - A TUMOR-MARKER IN NEPHROBLASTOMA

被引：25

作者：

CARACHI, R

LINDOP, GBM

LECKIE, BJ

机构：

[1] UNIV GLASGOW,DEPT PATHOL,GLASGOW G12 8QQ,SCOTLAND

[2] WESTERN INFIRM,MRC,BLOOD PRESSURE UNIT,GLASGOW G11 6NT,SCOTLAND

来源：

JOURNAL OF PEDIATRIC SURGERY | 1987年 / 22卷 / 03期

关键词：

nephroblastoma; Renin;

D O I：

10.1016/S0022-3468(87)80347-0

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Renin-containing cells have been identified in nephroblastoma. A prospective study of eight children with nephroblastoma has demonstrated abnormally high levels of total renin. The increase in total renin was due to increased levels of inactive renin (prorenin), rather than the active renin. These high levels decreased to normal after operation. The plasma level of inactive renin could be a useful biochemical tumor marker in nephroblastoma. © 1987 Grune & Stratton, Inc.

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页码：278 / 280

页数：3

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