CIRCULAR DICHROISM OF NUCLEOSIDE DERIVATIVES .4. URACIL DERIVATIVES

Circular dichroism data are reported for 16 uracil nucleoside derivatives especially designed to help determine the nature of the excited states of uridine and their energies. The interpretation of the spectra is facilitated by a comparison of the same electronic transition and its associated Cotton effect in different solvent media and different asymmetric environments. Cotton effects were resolved in the near-ultraviolet CD spectra which indicate the presence of electronic transitions not discovered by other spectroscopic techniques. Four optically active transitions were observed between 185 and 275 mμ. © 1969, American Chemical Society. All rights reserved.