Crystal and molecular structure of (9aS,10S)-6-Oxo-6,7,8,9,9a,10-hexahydro-4H-thieno-[2,3-b]quinolizin-10-yl acetate

被引：2

作者：

Vrabel, Viktor ^{[1
]}

Sivy, Julius ^{[2
]}

Safar, Peter ^{[3
]}

Marchalin, Stefan ^{[3
]}

机构：

[1] Slovak Tech Univ, Fac Chem & Food Technol, Inst Analyt Chem, Radlinskeho 9, SK-81237 Bratislava, Slovakia

[2] Slovak Univ Technologyy, Inst Math & Phys, Fac Mech Engn, Namestie Slobody 17, SK-81231 Bratislava, Slovakia

[3] Slovak Tech Univ, Fac Chem & Food Technol, Inst Organ Chem Catalysis & Petrochem, Radlinskeho 9, SK-81237 Bratislava, Slovakia

来源：

ACTA CHIMICA SLOVACA | 2016年 / 9卷 / 02期

关键词：

crystal structure; hydrogen interactions; quinolizine; single-crystal X-ray study;

D O I：

10.1515/acs-2016-0030

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title compound, C13H15NO3S, is a chiral molecule with two stereogenic centres. Its absolute configuration was derrived from the synthesis and confirmed by structure determination. The expected stereochemistry of atoms C5 and C6 was confirmed to be S. The central N-heterocyclic rings are not planar and adopt a half-chair conformation. A calculation of least-squares planes showed that these rings are puckered in such a manner that the five atoms C1, C2, C3, C5 and N1 (second ring: N1, C6, C7, C10 and C11) are planar, while atoms C4 (C5) are displaced from these planes with the out-of-plane displacement of 0.582 (3) A and 0,666 (2) angstrom in the second ring, respectively. Dihedral angle between the planes of the central N-heterocyclic rings is 40.0 (1)degrees. Crystal structure is stabilized by C-H center dot center dot center dot O hydrogen interactions.

引用

页码：180 / 183

页数：4

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