EFFECT OF 4 IV INDUCTION-AGENTS ON T-LYMPHOCYTE PROLIFERATIONS TO PHA IN-VITRO

被引：42

作者：

DEVLIN, EG ^{[1
]}

CLARKE, RSJ ^{[1
]}

MIRAKHUR, RK ^{[1
]}

MCNEILL, TA ^{[1
]}

机构：

[1] QUEENS UNIV BELFAST,DEPT IMMUNOL,BELFAST BT7 1NN,ANTRIM,NORTH IRELAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1994年 / 73卷 / 03期

关键词：

ANESTHETIC TECHNIQUES; IV BOLUS; BLOOD; LYMPHOCYTES;

D O I：

10.1093/bja/73.3.315

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Anaesthetic agents are believed to have an adverse effect on human immunity. We have studied the effects of four i.v. induction agents, thiopentone, methohexitone, etomidate and propofol, on T-lymphocyte proliferations to phytohaemagglutinin in vitro. We found that at plasma concentrations similar to those obtained after induction doses, all drugs, with the exception of propofol, caused depression of T-lymphocyte function.

引用

页码：315 / 317

页数：3

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