The impact of remifentanil on incidence and severity of postoperative nausea and vomiting in a university hospital-based ambulatory surgery center: a retrospective observation study

被引：10
作者：
Hara, Risa [1 ]
Hirota, Kiichi [1 ,2 ]
Sato, Masami [1 ]
Tanabe, Hiroko [1 ]
Yazawa, Tomoko [1 ]
Habara, Toshie [1 ]
Fukuda, Kazuhiko [1 ]
机构：
[1] Kyoto Univ Hosp, Dept Anesthesia, Sakyo Ku, 54 Shogoin Kawaharacho, Kyoto 6068507, Japan
[2] Kyoto Univ Hosp, Day Surg Unit, Kyoto, Japan
来源：
KOREAN JOURNAL OF ANESTHESIOLOGY | 2013年 / 65卷 / 02期
关键词：
Ambulatory surgery; Postoperative nausea and vomiting; Remifentanil;
D O I：
10.4097/kjae.2013.65.2.142
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Background: Ambulatory surgery, including short-stay surgery, has become a common choice in clinical practice. For the success of ambulatory surgery, perioperative care with safe and effective anesthesia and postoperative analgesia, which can reduce the occurrence of postoperative nausea and vomiting (PONV), is essential. The effect of remifentanil on the occurrence and severity of PONV has not been thoroughly examined, particularly, in an ambulatory surgery setting. Here, we investigate whether remifentanil influences the occurrence and severity of PONV in a university hospital-based ambulatory unit. Methods: We retrospectively analyzed a total of 1,765 cases of patients who had undergone general anesthesia at our ambulatory surgery unit. Parameters, such as occurrence and severity of nausea, vomiting or retching, use of antiemetic drugs, amount of postoperative analgesic and patient satisfaction, were extracted from the records and analyzed between the groups that received and not received remifentanil. Results: Within 565 patients of the RF group, 39 patients (6.6%) experienced nausea, 7 patients (1.2%) experienced vomiting or retching, and 10 patients (1.8%) were given antiemetic; in addition, the maximum VAS value for nausea was 12.1 mm. In 1,200 patients of the non RF group, 102 patients (8.5%) experienced nausea, 19 patients (1.6%) experienced vomiting or retching, and 34 patients (2.8%) were given antiemetic, and the maximum VAS value was 13.2 mm. There were no statistically significant differences between the two groups. Conclusions: Our results indicate that remifentanil did not increase the occurrence of PONV in patients within the ambulatory surgery unit.
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页码：142 / 146
页数：5
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共 11 条
  • [1] Shirakami G., Teratani Y., Namba T., Hirakata H., Tazuke-Nishimura M., Fukuda K., Delayed discharge and acceptability of ambulatory surgery in adult outpatients receiving general anesthesia, J Anesth, 19, pp. 93-101, (2005)
  • [2] Shirakami G., Teratani Y., Segawa H., Matsuura S., Shichino T., Fukuda K., Omission of fentanyl during sevoflurane anesthesia decreases the incidences of postoperative nausea and vomiting and accelerates postanesthesia recovery in major breast cancer surgery, J Anesth, 20, pp. 188-195, (2006)
  • [3] Koivuranta M., Laara E., Snare L., Alahuhta S., A survey of postoperative nausea and vomiting, Anaesthesia, 52, pp. 443-449, (1997)
  • [4] Gan T.J., Meyer T., Apfel C.C., Chung F., Davis P.J., Eubanks S., Et al., Consensus guidelines for managing postoperative nausea and vomiting, Anesth Analg, 97, pp. 62-71, (2003)
  • [5] Gan T.J., Meyer T.A., Apfel C.C., Chung F., Davis P.J., Habib A.S., Et al., Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting, Anesth Analg, 105, pp. 1615-1628, (2007)
  • [6] Apfel C.C., Korttila K., Abdalla M., Kerger H., Turan A., Vedder I., Et al., A factorial trial of six interventions for the prevention of postoperative nausea and vomiting, N Engl J Med, 350, pp. 2441-2451, (2004)
  • [7] Komatsu R., Turan A.M., Orhan-Sungur M., McGuire J., Radke O.C., Apfel C.C., Remifentanil for general anaesthesia: A systematic review, Anaesthesia, 62, pp. 1266-1280, (2007)
  • [8] Sato M., Shirakami G., Tazuke-Nishimura M., Matsuura S., Tanimoto K., Fukuda K., Effect of single-dose dexmedetomidine on emergence agitation and recovery profiles after sevoflurane anesthesia in pediatric ambulatory surgery, J Anesth, 24, pp. 675-682, (2010)
  • [9] Apfel C.C., Roewer N., Korttila K., How to study postoperative nausea and vomiting, Acta Anaesthesiol Scand, 46, pp. 921-928, (2002)
  • [10] Minto C.F., Schnider T.W., Shafer S.L., Pharmacokinetics and pharmacodynamics of remifentanil. II. Model application, Anesthesiology, 86, pp. 24-33, (1997)
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