MUTATIONS ON THE 2ND CHROMOSOME AFFECTING THE DROSOPHILA EYE

被引:21
作者
BAKER, NE
MOSES, K
NAKAHARA, D
ELLIS, MC
CARTHEW, RW
RUBIN, GM
机构
[1] UNIV CALIF BERKELEY,DEPT MOLEC & CELL BIOL,BERKELEY,CA 94720
[2] UNIV CALIF BERKELEY,HOWARD HUGHES MED INST,BERKELEY,CA 94720
关键词
DROSOPHILA EYE; GENETIC SCREEN; PATTERN FORMATION; CELL INTERACTIONS;
D O I
10.3109/01677069209084154
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
In the developing eye of Drosophila, cell interactions appear to be responsible for organising undifferentiated cells into unit eyes, or ommatidia. Extensive mutagenesis has been used to search for mutations affecting the development and differentiation of ommatidia. These mutations have been characterized using sections of adults and immunocytochemistry of imaginal discs. Fourteen loci on the second chromosome are described that affect the spacing of the preclusters, the differentiation of ommatidial cells, orientation of the ommatidia, or architecture of the adult retina, that cause retinal degeneration in larval or pupal eye discs, or that cause homeotic transformation of part of the head. © 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
引用
收藏
页码:85 / 100
页数:16
相关论文
共 47 条
[11]   HEREDITARY RETINAL DEGENERATION IN DROSOPHILA-MELANOGASTER - MUTANT DEFECT ASSOCIATED WITH PHOTO-TRANSDUCTION PROCESS [J].
HARRIS, WA ;
STARK, WS .
JOURNAL OF GENERAL PHYSIOLOGY, 1977, 69 (03) :261-291
[12]  
Hochman B, 1976, GENET BIOL DROSOPHIL, P903
[13]  
HOTTA Y, 1970, P NATL ACAD SCI USA, V67, P11561
[14]  
Lewis E.B., 1968, DROSOPHILA INFO SERV, V43, P193
[15]  
LIND JH, 1990, SLAVON E EUR REV, V68, P1
[16]  
LINDSLEY DL, 1968, CARNEGIE I WASH PUBL, V627
[17]   GENE ENCODING CYTOSKELETAL PROTEINS IN DROSOPHILA RHABDOMERES [J].
MATSUMOTO, H ;
ISONO, K ;
PYE, Q ;
PAK, WL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (04) :985-989
[18]   PATTERN-FORMATION DURING ANIMAL DEVELOPMENT [J].
MELTON, DA .
SCIENCE, 1991, 252 (5003) :234-241
[19]   GENETIC-ANALYSIS OF VISUAL-SYSTEM DEVELOPMENT IN DROSOPHILIA-MELANOGASTER [J].
MEYEROWITZ, EM ;
KANKEL, DR .
DEVELOPMENTAL BIOLOGY, 1978, 62 (01) :112-142
[20]   ISOLATION AND EXPRESSION OF SCABROUS, A GENE REGULATING NEUROGENESIS IN DROSOPHILA [J].
MLODZIK, M ;
BAKER, NE ;
RUBIN, GM .
GENES & DEVELOPMENT, 1990, 4 (11) :1848-1861