PURINE N-OXIDES .25. 3-N-OXIDES OF ADENINE AND HYPOXANTHINE

被引:28
作者
SCHEINFELD, I
PARHAM, JC
MURPHY, S
BROWN, GB
机构
[1] Division of Biological Chemistry, Sloan-Ketiering Institute for Cancer Research, Sloan-Kettering Division, Graduate School of Medical Sciences, Cornell University Medical College, New York
关键词
D O I
10.1021/jo01259a027
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The 3-N-oxides of adenine, hypoxanthine, and 6-methoxypurine are synthesized by displacements of the sulfonyl group of 6-sulfonylpurine 3-oxides. The latter is obtained from 6-mercaptopurine 3-oxide, as are the corresponding sulfinyl-, methylsulfonyl-, and disulfide derivatives. An oxidation product of 6-methoxypurine is shown to be the 3-N-oxide. © 1969, American Chemical Society. All rights reserved.
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页码:2153 / +
页数:1
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