MOLECULAR-BASES FOR THE CONSTRUCTION OF ARTIFICIAL IMMUNOGENS AND VACCINES BASED ON SYNTHETIC POLYIONS

被引：2
|
作者：
KHAITOV, RM [1 ]
机构：
[1] MINIST HLTH,INST IMMUNOL,NATL RES CTR,MOSCOW,RUSSIA
来源：
ALLERGY PROCEEDINGS | 1995年 / 16卷 / 05期
关键词：
D O I：
10.2500/108854195778702648
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
The molecular and cellular mechanisms of action of synthetic polyions on immunogenesis are reviewed. The results of studies of principal properties of polyionic immunostimulators and of the cell responses to the action of these stimulants have been used to construct artificial antigen-polyion complexes with enhanced immunogenic properties. The immunizing properties of such macromolecular complexes, constructed with the use of bacterial or viral antigens, are analyzed.
引用
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页码：255 / 260
页数：6
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