ORBITO-OCULAR GRANULOCYTIC SARCOMA (OOGS) AND ACUTE MYELOBLASTIC-LEUKEMIA (AML) WITH DUPLICATION OF PHILADELPHIA-CHROMOSOME

被引：4

作者：

CAVDAR, AO

BOKESOY, I

SUNGUROGLU, A

YAVUZ, G

TANINDI, S

GOZDASOGLU, S

BABACAN, E

PAMIR, A

UNAL, E

TURKER, A

机构：

[1] UNIV ANKARA,PEDIAT HEMATOL ONCOL RES CTR,ANKARA,TURKEY

[2] UNIV ANKARA,DEPT MED BIOL,ANKARA,TURKEY

[3] GULHANE MIL MED ACAD,ANKARA,TURKEY

来源：

CANCER GENETICS AND CYTOGENETICS | 1993年 / 69卷 / 01期

关键词：

D O I：

10.1016/0165-4608(93)90110-8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 6-year-old Turkish boy with bilateral orbito-ocular granulocytic sarcoma and AML is described. Cytogenetic studies on peripheral blood disclosed an abnormal hyperdiploid population with a double Ph chromosome. Despite intensive chemotherapy, he achieved only partial remission. Repeated cytogenetic studies on bone marrow during relapse revealed the persistence of double Ph chromosome. The aggressive course and the short survival time of this patient, despite adequate chemo-radiotherapy, may be explained by the presence of the double Ph chromosome.

引用

页码：38 / 40

页数：3

共 11 条

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ABE R, 1986, CANCER, V58, P1260, DOI 10.1002/1097-0142(19860915)58:6<1260::AID-CNCR2820580614>3.0.CO

[2]

2-O

[3] PHILADELPHIA-POSITIVE ACUTE-LEUKEMIA - CYTOGENETIC AND MOLECULAR ASPECTS [J].