STRUCTURAL STUDIES OF THE VIBRIO-CHOLERAE O-3 O-ANTIGEN POLYSACCHARIDE

被引：37

作者：

CHOWDHURY, TA ^{[1
]}

JANSSON, PE ^{[1
]}

LINDBERG, B ^{[1
]}

LINDBERG, J ^{[1
]}

GUSTAFSSON, B ^{[1
]}

HOLME, T ^{[1
]}

机构：

[1] KAROLINSKA INST, DEPT BACTERIOL, S-10401 STOCKHOLM 60, SWEDEN

来源：

CARBOHYDRATE RESEARCH | 1991年 / 215卷 / 02期

关键词：

D O I：

10.1016/0008-6215(91)84029-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of the Vibrio cholerae O:3 O-antigen polysaccharide has been investigated, mainly by n.m.r. spectroscopy, mass spectrometry, sugar and methylation analysis, and specific degradations, and is proposed to involve the following tetrasaccharide repeating-unit. [GRAPHICS] In this structure, D-D-Hep is D-glycero-D-manno-heptose, Asc is 3,6-dideoxy-L-arabino-hexose (ascarylose), and Sug is 2,4-diamino-2,4,6-trideoxy-D-glucose (bacillosamine) in which N-2 is acetylated and N-4 is acylated with a 3,5-dihydroxyhexanoic acid. That the 2,4-diamino-2,4,6-trideoxy-D-glucose residue is linked through O-3 and not through one of the hydroxyl groups in the 3,5-dihydroxyhexanoyl group is indicated but not definitely proved. The configuration of the latter group has not been determined. The f.a.b.-mass spectrum of the methylated O-antigen indicates that the structure given above also represents the biological repeating-unit.

引用

页码：303 / 314

页数：12

共 15 条

[1] STRUCTURAL STUDIES OF THE O-ANTIGEN FROM VIBRIO-CHOLERAE O-21
ALIANSARI, A
KENNE, L
LINDBERG, B
GUSTAFSSON, B
HOLME, T
[J]. CARBOHYDRATE RESEARCH, 1986, 150 (01) : 213 - 219
[2] OPTIMIZATION OF 2-DIMENSIONAL HOMONUCLEAR RELAYED COHERENCE TRANSFER NMR-SPECTROSCOPY
BAX, A
DROBNY, G
[J]. JOURNAL OF MAGNETIC RESONANCE, 1985, 61 (02) : 306 - 320
[3] DETERGENT-ACCELERATED HYDROLYSIS OF BACTERIAL-ENDOTOXINS AND DETERMINATION OF THE ANOMERIC CONFIGURATION OF THE GLYCOSYL PHOSPHATE PRESENT IN THE ISOLATED LIPID-A FRAGMENT OF THE BORDETELLA-PERTUSSIS ENDOTOXIN
CAROFF, M
TACKEN, A
SZABO, L
[J]. CARBOHYDRATE RESEARCH, 1988, 175 (02) : 273 - 282
[4] FAB-MASS SPECTROMETRY OF CARBOHYDRATES
DELL, A
[J]. ADVANCES IN CARBOHYDRATE CHEMISTRY AND BIOCHEMISTRY, 1987, 45 : 19 - 72
[5] DETERMINATION OF D AND L CONFIGURATION OF NEUTRAL MONOSACCHARIDES BY HIGH-RESOLUTION CAPILLARY GLC
GERWIG, GJ
KAMERLING, JP
VLIEGENTHART, JFG
[J]. CARBOHYDRATE RESEARCH, 1978, 62 (02) : 349 - 357
[6] 2-AMINO-2,6-DIDEOXY-D-GLUCOSE (D-QUINOVOSAMINE) - CONSTITUENT OF LIPOPOLYSACCHARIDES OF VIBRIO-CHOLERAE
JANN, B
JANN, K
BEYAERT, GO
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 37 (03): : 531 - 534
[7] THE CELL-WALL ANTIGEN FROM EUBACTERIUM-SABURREUM STRAIN-L13, A NEW TYPE OF BIO-POLYMER
JANSSON, PE
LINDBERG, B
SPELLMAN, M
HOFSTAD, T
SKAUG, N
[J]. CARBOHYDRATE RESEARCH, 1985, 137 (MAR) : 197 - 203
[8] STRUCTURAL STUDIES OF THE VIBRIO CHOLERAE O-ANTIGEN
KENNE, L
LINDBERG, B
UNGER, P
GUSTAFSSON, B
HOLME, T
[J]. CARBOHYDRATE RESEARCH, 1982, 100 (MAR) : 341 - 349
[9] Structural studies of the O-antigen from Vibrio cholerae O : 2
Kenne, Lennart
Lindberg, Bengt
Schweda, Elke
Gustafsson, Bjoern
Holme, Tord
[J]. CARBOHYDRATE RESEARCH, 1988, 180 (02) : 285 - 294
[10] SOMATIC ANTIGENS OF PSEUDOMONAS-AERUGINOSA - THE STRUCTURE OF O-SPECIFIC POLYSACCHARIDE CHAINS OF P-AERUGINOSA-O-10 (LANYI) LIPOPOLYSACCHARIDES
KNIREL, YA
VINOGRADOV, EV
SHASHKOV, AS
DMITRIEV, BA
KOCHETKOV, NK
STANISLAVSKY, ES
MASHILOVA, GM
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1986, 157 (01): : 129 - 138

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