THE EFFECT OF CHAIN EXTENDERS AND STABILIZERS ON THE INVIVO STABILITY OF POLYURETHANES

被引：23

作者：

HERGENROTHER, RW ^{[1
]}

WABERS, HD ^{[1
]}

COOPER, SL ^{[1
]}

机构：

[1] UNIV WISCONSIN,DEPT CHEM ENGN,1415 JOHNSON DR,MADISON,WI 53706

来源：

JOURNAL OF APPLIED BIOMATERIALS | 1992年 / 3卷 / 01期

关键词：

D O I：

10.1002/jab.770030104

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Poly(etherurethane) (PEU) and poly(etherurethaneurea) (Biomer(R)) films with and without antioxidant stabilizers were subcutaneously implanted into dogs and rats for up to 10 weeks. It was found that the molecular weight of the PEU films decreased over the 10-week period, while the Biomer(R) films increased in molecular weight. The presence of the stabilizers resulted in less severe changes in molecular weight. Surface cracking was most pronounced on both the stabilized and nonstabilized PEU films. Stress did not have to be applied to induce the surface cracking.

引用

页码：17 / 22

页数：6

共 16 条

[1] COMPOSITIONAL ANALYSIS OF BIOMER
BELISLE, J
MAIER, SK
TUCKER, JA
[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1990, 24 (12): : 1585 - 1598
[2] SEGMENTED POLYURETHANE - A NEW ELASTOMER FOR BIOMEDICAL APPLICATIONS
BORETOS, JW
PIERCE, WS
[J]. SCIENCE, 1967, 158 (3807) : 1481 - &
[3] SURFACE-PROPERTIES AND BLOOD COMPATIBILITY OF POLYURETHANEUREAS
GRASEL, TG
COOPER, SL
[J]. BIOMATERIALS, 1986, 7 (05) : 315 - 328
[4] SYNTHESIS AND CHARACTERIZATION OF MDI-BUTANEDIOL URETHANE MODEL COMPOUNDS
HWANG, KKS
WU, GS
LIN, SB
COOPER, SL
[J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 1984, 22 (07) : 1677 - 1697
[5] THIN POLYMER-FILMS FOR TRANSMISSION INFRARED SPECTROSCOPY
KOBERSTEIN, JT
COOPER, SL
SHEN, MC
[J]. REVIEW OF SCIENTIFIC INSTRUMENTS, 1975, 46 (12) : 1639 - 1641
[6] Lelah M. D., 1986, POLYURETHANES MED
[7] ANALYSIS OF INVITRO ENZYMATIC AND OXIDATIVE-DEGRADATION OF POLYURETHANES
RATNER, BD
GLADHILL, KW
HORBETT, TA
[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1988, 22 (06): : 509 - 527
[8] SAUNDERS JH, 1960, POLYURETHANES CHEM T
[9] THE BIODEGRADATION OF POLY(ETHER URETHANES)
SMITH, R
WILLIAMS, DF
OLIVER, C
[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1987, 21 (09): : 1149 - 1165
[10] STOKES K, 1987, POLYURETHANES BIOMED, V2, P109

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