IDENTIFICATION OF TEM-26 BETA-LACTAMASE RESPONSIBLE FOR A MAJOR OUTBREAK OF CEFTAZIDIME-RESISTANT KLEBSIELLA-PNEUMONIAE

被引：58
作者：
URBAN, C
MEYER, KS
MARIANO, N
RAHAL, JJ
FLAMM, R
RASMUSSEN, BA
BUSH, K
机构：
[1] NYU,SCH MED,DEPT MICROBIOL,NEW YORK,NY 10016
[2] ALBERT EINSTEIN COLL MED,NEW YORK,NY 10461
[3] BRISTOL MYERS SQUIBB CO,DEPT MICROBIOL,WALLINGFORD,CT 06492
[4] AMER CYANAMID CO,DIV MED RES,PEARL RIVER,NY 10965
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 02期
关键词：
D O I：
10.1128/AAC.38.2.392
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
An epidemic of nosocomial ceftazidime-resistant Klebsiella pneumoniae was correlated with production of a ceftazidime-hydrolyzing enzyme with an isoelectric point of 5.6 (BMH-1). BMH-1 was encoded on a large transferable plasmid conferring multiple antibiotic resistance. The gene that encodes BMH-1 was identical to the gene that encodes the TEM-26 extended-spectrum beta-lactamase.
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页码：392 / 395
页数：4
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