PERSISTENCE OF CONTRACTILE BEHAVIOUR IN ACUTELY ISCHAEMIC MYOCARDIUM

被引：100

作者：

HOOD, WB

COVELLI, VH

ABELMANN, WH

NORMAN, JC

机构：

[1] Thorndike Memorial Laboratory, Second and Fourth (Harvard) Medical Services, Sears Surgical Laboratory, Harvard Surgical Service, Departments of Medicine and Surgery, Harvard Medical School, Boston City Hospital, Boston, MA

来源：

CARDIOVASCULAR RESEARCH | 1969年 / 3卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/cvr/3.3.249

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Authors' Synopsis: Experiments were performed in pigs and dogs which showed that myocardium rendered acutely ischaemic by occluding the left anterior descending coronary artery nonetheless maintained contractile behaviour. The ischaemic myocardium responded to both positive and negative inotropic agents, and, despite aneurysmal dilatation during systole, was less distensible than at necropsy. These effects could be quantitated by application of force-velocity relationships.

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页码：249 / &

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