HYPERCALCIURIA AND NEPHROCALCINOSIS IN PATIENTS WITH IDIOPATHIC LOW-MOLECULAR-WEIGHT PROTEINURIA IN JAPAN - IS THE DISEASE IDENTICAL TO DENTS DISEASE IN UNITED-KINGDOM

被引：58

作者：

IGARASHI, T

HAYAKAWA, H

SHIRAGA, H

KAWATO, H

YAN, K

KAWAGUCHI, H

YAMANAKA, T

TSUCHIDA, S

AKAGI, K

机构：

[1] CHILDRENS HOSP,DIV NEPHROL,CHIBA,JAPAN

[2] METROPOLITAN HACHIOHJI CHILDRENS HOSP,DEPT PEDIAT,HACHIOJI,TOKYO,JAPAN

[3] MITSUI MEM HOSP,DEPT PEDIAT,TOKYO,JAPAN

[4] MUNICIPAL GEN HOSP,DEPT PEDIAT,YAIZU,JAPAN

[5] TORANOMON GEN HOSP,DEPT PEDIAT,TOKYO,JAPAN

来源：

NEPHRON | 1995年 / 69卷 / 03期

关键词：

HYPERCALCIURIA; NEPHROCALCINOSIS; IDIOPATHIC LOW-MOLECULAR-WEIGHT PROTEINURIA; DENTS DISEASE;

D O I：

10.1159/000188464

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Idiopathic low-molecular-weight (LMW) proteinuria is a newly described renal disease in Japan and Italy, We report on 7 patients who manifested bilateral or unilateral nephrocalcinosis, as demonstrated by abdominal computed tomography scans. Renal histology revealed calcinosis of renal tubules in 2 patients, Computed tomography is a reliable method for the detection of nephrocalcinosis in this disorder. Hypercalciuria was also seen in 6 patients, A calcium-loading test performed in 2 patients suggested that hypercalciuria was of renal origin, Although the true pathogenesis is still not known, hypercalciuria and nephrocalcinosis appear to be a common complication in patients with idiopathic LMW proteinuria. These complications and clinical features suggest that idiopathic LMW proteinuria in Japan is likely to be identical to Dent's disease in the United Kingdom.

引用

页码：242 / 247

页数：6

共 16 条

[1] DIFFUSE NEPHROCALCINOSIS AND IDIOPATHIC RENAL HYPERCALCIURIA [J].