EFFICACY AND SPECIFICITY OF PHARMACOLOGICAL THERAPIES FOR BEHAVIORAL-DISORDERS IN PERSONS WITH MENTAL-RETARDATION

被引：57

作者：

BAUMEISTER, AA ^{[1
]}

TODD, ME ^{[1
]}

SEVIN, JA ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,KENNEDY KRIEGER INST,DEPT BEHAV PSYCHOL,BALTIMORE,MD 21205

来源：

CLINICAL NEUROPHARMACOLOGY | 1993年 / 16卷 / 04期

关键词：

DRUGS; MENTAL RETARDATION; NEUROLEPTICS; SELF-INJURIOUS BEHAVIOR; HYPERACTIVITY; AGGRESSION; STEREOTYPED BEHAVIOR; NALTREXONE;

D O I：

10.1097/00002826-199308000-00001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This review assesses the efficacy and specificity of psychotropic medications used to control aberrant behavior in persons with mental retardation. It is concluded that neuroleptics the most widely used psychotropic agents in this population, suppress aberrant behavior, but do so by suppressing behavior generally. An exception to this conclusion is that it may be possible to selectively suppress stereotyped behavior with neuroleptics. In addition, the empirical evidence indicates that, in some persons with mental retardation, opioid antagonists and methylphenidate are useful therapies for self-injurious behavior and hyperactivity, respectively. Lithium and beta-blockers are potentially useful for treating aggression.

引用

页码：271 / 294

页数：24

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