AGE-DIFFERENCES AND STRESS-ULCER IN THE RAT

被引：18
作者：
PARE, WP
VINCENT, GP
ISOM, KE
机构：
[1] Pavlovian Research Laboratory, Veterans Administration Medical Center, Perry Point, MD
来源：
EXPERIMENTAL AGING RESEARCH | 1979年 / 5卷 / 01期
关键词：
D O I：
10.1080/03610737908257186
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
Rats 2-, 7- and 12- mo. old were exposed to supine body restraint plus cold (5°C) for 3 hr. The mean cumulative length of lesions for the 2-, 7-, and 12 mo. old rats was 22.0, 43.0 and 16.0 mm. respectively. The same experimental design was used in a second study, but the pylorus was ligated prior to restraint. Total acid output/hr. was 134.6, 178.2, and 64.7 μEq/60 min. respectively for the three age groups. Older rats were not more susceptible to stress-ulcer and gastric acid was not significantly related to degree of ulceration. © 1979 Taylor & Francis Group, LLC.
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页码：31 / 42
页数：12
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