Reduction of machine downtime in the production of agricultural work is possible due to the harmonization of the phases of the process in terms of productivity, reducing technological gaps during harvesting, which reduces the parametric and functional failures of the technological system in question. As a result, the cost of grain is reduced and the balanced result of the economic activities of the agricultural organization is improved. For the engineering and technical subsystem of the agricultural organization, the most urgent issue is ensuring the continuity of the operation of agricultural machinery. Topical issues of the effectiveness of technological processes for the production of agricultural crop production due to the consistency, of the machine and tractor fleet performance, subject to maintenance of technical readiness at a regulated level. In connection with the increasing complexity of tractors, grain harvesters and other combines, agricultural machinery and machine-tractor units, the task of operating this technique can be solved more efficiently using information technologies based on mathematical modeling. The rational organization of the technological system of machine operation during the harvesting of grain crops on the basis of mathematical modeling will reduce the parametric and functional failures and increase the efficiency of the use of technical means. Based on the simulation system of discrete GPSS systems at the University of Michigan, it was planned to develop a formalized scheme, a mathematical model, and a simulation algorithm. A mathematical model of a system for the operation of combine harvesters, tractors and agricultural machines during the harvesting period of grain crops is proposed. The use of this method will make it possible to justify the economically expedient level of loading and productivity in the phases of the harvesting process. The mathematical model is the basis for improving the efficiency indicators of the use of technological processes for harvesting grain crops.