OPTICALLY PURE AND FLUORO SUBSTITUTED CARBOACYCLIC NUCLEOSIDE ANALOGS

被引：13

作者：

BRAVO, P

FRIGERIO, M

SOLOSHONOK, V

VIANI, F

机构：

[1] CNR - Centro, Studio per le Sostanze Organiche Naturali - Dipartimento di Chimica, Politecnico di Milano, I-20131 Milano

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 48期

关键词：

D O I：

10.1016/S0040-4039(00)61562-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Fluorinated analogues of carboacyclic nucleosides are obtained in optically pure form starting from homochiral epoxides through nitrogen nucleophilic opening of the oxirane ring.

引用

页码：7771 / 7772

页数：2

共 5 条

[1] NUCLEOCYCLITOLS - SYNTHESIS OF SUBSTITUTED PURINYL-MUCO-INOSITOL DERIVATIVES [J].

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JOURNAL OF HETEROCYCLIC CHEMISTRY, 1992, 29 (02) :401-405

[2] A NEW VERSATILE FLUORINATED-C(4) CHIRON [J].

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TETRAHEDRON LETTERS, 1992, 33 (38) :5609-5612

[3] GENERAL-SYNTHESIS OF CARBANUCLEOSIDES VIA REGIOSPECIFIC EPOXIDE OPENING BY THE AGLYCONE [J].

BAUMGARTNER, H ;

MARSCHNER, C ;

PUCHER, R ;

GRIENGL, H .

TETRAHEDRON LETTERS, 1991, 32 (05) :611-614

[4] OPTICALLY PURE AND FLUOROSUBSTITUTED ACYCLOVIR ANALOGS [J].

BRAVO, P ;

RESNATI, G ;

VIANI, F .

TETRAHEDRON, 1993, 49 (03) :713-720

[5] SYNTHESIS OF HYDROXYLATED CYCLOHEXENYLADENINES AND CYCLOHEXANYLADENINES AS POTENTIAL INHIBITORS OF S-ADENOSYLHOMOCYSTEINE HYDROLASE [J].

RAMESH, K ;

WOLFE, MS ;

LEE, Y ;

VELDE, DV ;

BORCHARDT, RT .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (22) :5861-5868

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