PERITONEAL MORPHOLOGY IN CHILDREN TREATED BY CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS

被引：32

作者：

SCHNEBLE, F ^{[1
]}

BONZEL, KE ^{[1
]}

WALDHERR, R ^{[1
]}

BACHMANN, S ^{[1
]}

ROTH, H ^{[1
]}

SCHARER, K ^{[1
]}

机构：

[1] UNIV HEIDELBERG,DEPT PAEDIAT,W-6900 HEIDELBERG,GERMANY

来源：

PEDIATRIC NEPHROLOGY | 1992年 / 6卷 / 06期

关键词：

PERITONEAL DIALYSIS; PERITONEUM; PERITONITIS; UREMIA; SCANNING ELECTRON MICROSCOPY;

D O I：

10.1007/BF00866498

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Fifty peritoneal biopsies (PB) from 35 patients with end-stage renal disease, treated by continuous ambulatory peritoneal dialysis (CAPD) and aged 2 months to 18 years, were examined by light microscopy (n = 50) and/or scanning electron microscopy. PB were performed during surgical procedures immediately before the start of, during, or after the cessation of CAPD treatment. PB from 15 children without renal disease undergoing laparatomy were examined similarly. Before the start of CAPD, a scarcity and shortening of the mesothelial microvilli was observed by scanning electron microscopy. During and after CAPD, variable alterations of mesothelium, interstitium and capillaries were found. The mesothelial layer was absent in all 5 PB obtained during episodes of active peritonitis. In patients treated by CAPD for longer than 6 months, mesothelial denudation was observed more frequently (6/11) than in children treated for shorter periods (1/7) (P <0.08). Fibrosis of the peritoneal membrane was present in about 50% of patients during or after the cessation of CAPD without impairment of peritoneal function. No correlation was found between the presence of fibrosis and the frequency of peritonitis or the duration of CAPD treatment.

引用

页码：542 / 546

页数：5

共 27 条

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